About BRIGX

Overview

BRIGX (BLAST Ring Image Generator eXtended) is a web-based tool for comparative genomics visualization. It creates circular genome comparison plots similar to the original BRIG tool, but runs entirely in your browser using WebAssembly technology.

Features

  • Compare multiple genome sequences against a reference genome
  • Interactive circular visualization with multiple rings
  • GC content and GC skew analysis
  • Configurable alignment parameters
  • Export results as SVG or PNG
  • Download alignment results for each ring
  • All processing happens locally in your browser

How It Works

BRIGX uses BLAST (Basic Local Alignment Search Tool), compiled to WebAssembly. This allows sophisticated bioinformatics analysis to run directly in your web browser without requiring any server-side processing or data upload.

Privacy

All processing happens locally in your browser using WebAssembly. Your genome data never leaves your computer, ensuring complete privacy and security of your research data.

Technology Stack

  • BLAST: Sequence alignment (formatdb + blastn)
  • WebAssembly: High-performance browser execution
  • Next.js: React framework for the user interface
  • Web Workers: Parallel processing for faster alignments

Citation

If you use BRIGX in your research, please cite the original BRIG paper:

Alikhan NF, Petty NK, Ben Zakour NL, Beatson SA (2011) BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons. BMC Genomics 12:402. Read the paper

Contributing

BRIGX is an open-source project. You can contribute to the project on GitHub.

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